Christie Clinic - Medicine for Your Life

Our website is currently having technical difficulties. To view the site, please click here

Health Encyclopedia

Health Encyclopedia

An invaluable resource of health information.

Cystinuria

Cystinuria is a condition passed down through families in which stones form in the kidney, ureter, and bladder.

See also: Nephrolithiasis

  • Alternative Names

    Stones - cystine; Cystine stones

  • Causes, incidence, and risk factors

    Cystinuria is an autosomal recessive disorder, so you must inherit the faulty gene from both parents in order to have symptoms.

    Cystinuria is caused by too much of an amino acid called cystine in the urine. After entering the kidneys, most cystine normally dissolves and goes back into the bloodstream. But people with cystinuria have a genetic defect that interferes with this process. As a result, cystine builds up in the urine and forms crystals or stones, which may get stuck in the kidneys, ureters, or bladder.

    About one in every 10,000 people have cystinuria. Cystine stones are most common in young adults under age 40. Less than 3% of urinary tract stones are cystine stones.

  • Symptoms
    • Blood in the urine
    • Flank pain or pain in the side or back
      • Usually on one side; rarely felt on both sides
      • Often severe
      • May get increasingly worse over days
      • Pain may also be felt in the pelvis, groin, genitals, or between the upper abdomen and the back.
  • Signs and tests

    The disorder is usually diagnosed after an episode of kidney stones. Analysis of the stones shows they are made of cystine.

    Tests that may be done to detect stones and diagnose this condition include:

  • Treatment

    The goal of treatment is to relieve symptoms and prevent the development of more stones. A person with severe symptoms may need to be admitted to a hospital.

    Treatment involves drinking plenty of fluids, particularly water, so that large amounts of urine are produced. The patient should drink at least 6-8 glasses per day.

    In some cases, fluids may need to be given through a vein (by IV).

    Medications may be prescribed to help dissolve the cystine crystals. Eating less salt can also decrease cystine excretion and stone formation.

    Pain relievers may be needed to control pain in the kidney or bladder area associated with the passage of stones. The stones usually pass through the urine on their own. If they do not, surgery may be needed:

  • Expectations (prognosis)

    Cystinuria is a chronic, lifelong condition. Stones commonly return. However, the condition rarely results in kidney failure, and it does not affect other organs.

  • Complications
  • Calling your health care provider

    Call your health care provider if you have symptoms of urinary tract stones.

  • Prevention

    There is no known prevention for cystinuria. Any person with a known history of stones in the urinary tract should drink plenty of fluids to regularly produce a high amount of urine. This allows stones and crystals to leave the body before they become large enough to cause symptoms.

  • References
    Rogers A, Kalakish S, Desai RA, Assimos DG. Management of cystinuria. Urol Clin North Am. 2007;34(3).

Review Date: 8/30/2009

Reviewed By: Louis S. Liou, MD, PhD, Assistant Professor of Urology, Department of Surgery, Boston University School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2014 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
adam.com
Christie Clinic Christie Clinic at the Family Medical Center in Paris Photo Christie Clinic at the Family Medical Center in Paris
727 East Court Street Paris, IL 61944 Dermatology: 366-1248; Vein and Vascular: 366-2670
Christie Clinic Christie Clinic on University Photo Christie Clinic on University
101 West University Avenue Champaign, IL 61820 Main Phone: (217) 366-1200
Billing Services: (217) 366-1382
Toll Free: (888) 391-0412
Christie Clinic Christie Clinic on Windsor/Convenient Care Photo Christie Clinic on Windsor/Convenient Care
1801 West Windsor Road Champaign, IL 61822 (217) 366-8000
Christie Clinic Christie Clinic at Presence Covenant Photo Christie Clinic at Presence Covenant
1400 West Park Street Urbana, IL 61801 (217) 366-1200
Christie Clinic Christie Clinic in Rantoul Photo Christie Clinic in Rantoul
209 West Borman Drive Rantoul, IL 61866 (217) 892-9671
Christie Clinic Christie Clinic in Mahomet/Convenient Care Photo Christie Clinic in Mahomet/Convenient Care
1001 Commercial Drive Mahomet, IL 61853 Main Number: (217) 586-6600 Convenient Care: (217)366-8130
Christie Clinic Christie Clinic in Tuscola Photo Christie Clinic in Tuscola
300 North Main Street Tuscola, IL 61953 (217) 253-9258
Christie Clinic CU Sleep Photo CU Sleep
1207 South Mattis Avenue Champaign, IL 61821 (217) 355-1684
Christie Clinic Christie Clinic Cancer Center Photo Christie Clinic Cancer Center
109 West University Avenue Champaign, IL 61820 (217) 366-5180
Christie Clinic Convenient Care in County Market (Kirby & Duncan) Photo Convenient Care in County Market (Kirby & Duncan)
2901 West Kirby Avenue Champaign, IL 61821 (217) 366-8130
Christie Clinic Christie Clinic in Urbana/Convenient Care Photo Christie Clinic in Urbana/Convenient Care
1710 East Windsor Road Urbana, IL 61802 (217) 344-9440
Christie Clinic Christie Clinic in Danville on Logan Photo Christie Clinic in Danville on Logan
800 North Logan Avenue Danville, IL 61832 (217) 431-8930
Christie Clinic Christie Clinic on Fox Drive Photo Christie Clinic on Fox Drive
2110 Fox Drive, Suite B Champaign, IL 61820
Christie Clinic Christie Clinic in Monticello at Kirby Medical Group Specialty Clinic Photo Christie Clinic in Monticello at Kirby Medical Group Specialty Clinic
1109 B North State Street Monticello, IL 61856 (217) 366-1304
Gibson Area Hospital
1120 N Melvin Gibson City, IL 60936 (217) 784-2240
Christie Clinic Christie Clinic in Mattoon Photo Christie Clinic in Mattoon
105 B Professional Plaza Mattoon, IL 61938 (217) 345-3000
Christie Clinic Sarah Bush Lincoln Health System Photo Sarah Bush Lincoln Health System
1000 Health Center Drive Mattoon, IL 61938 (217) 258-2588
Christie Clinic The Champaign SurgiCenter Photo The Champaign SurgiCenter
1702 S. Mattis Avenue Champaign, IL 61821 (217) 326-2030
Christie Clinic The Carle Foundation Hospital Photo The Carle Foundation Hospital
611 West Park Street Urbana, IL 61801 (217) 383-3311
Iroquois Memorial Hospital
200 E. Fairman Ave. Watseka, IL 60970 (815) 432-5841
Christie Clinic Christie Clinic in Savoy Photo Christie Clinic in Savoy
501 North Dunlap Avenue Savoy, IL 61874 Transformations: (217) 366-7460 Internal Medicine: (217) 366-5434 Ophthalmology: (217) 366-1250
Christie Clinic on West Park Street
1405 West Park Street Urbana, IL 61801 217-366-1237
Christie Clinic in Monticello
107 West Main Street Monticello, IL 61856 217.762.3352
Christie Clinic Christie Clinic in Decatur Photo Christie Clinic in Decatur
100 South Water Street Suite 103 Decatur, IL 62523 217-362-0661- telephone
Christie Clinic Christie Clinic in Danville on Vermilion/Convenient Care Photo Christie Clinic in Danville on Vermilion/Convenient Care
3545 North Vermilion Street Danville, IL 61832 (217) 442-8611