Patent foramen ovale

• Alternative Names

  PFO

• Causes, incidence, and risk factors

  A foramen ovale allows blood to bypass the lungs. A baby's lungs are not used when it grows in the womb, so the hole does not cause problems in an unborn infant. The opening is supposed to close soon after birth, but sometimes it does not. In about 1 out of 4 people, the opening never closes. If it does not, it is called a patent foramen ovale (PFO).

  The cause of a PFO is unknown. There are no known risk factors.

• Symptoms

  Infants with a patent foramen ovale and no other heart defects do not have symptoms.

• Signs and tests

  An echocardiogram can be done to diagnose a PFO. If the PFO is not easily seen, a cardiologist can perform a "bubble test." Saline solution (salt water) is injected into the body as the cardiologist watches the heart on an ultrasound (echocardiogram) monitor. If a PFO exists, tiny air bubbles will be seen moving from the right to left side of the heart.

• Treatment

  This condition is not treated unless other heart abnormalities exist or if you had a stroke caused by a blood clot to the brain.

  Treatment usually requires cardiac cathertization by a specifically trained cardiologist to permanently seal the PFO.

• Expectations (prognosis)

  The infant will have normal health in the absence of other heart defects.

• Complications

  Unless there are other associated defects, there are usually no complications associated with a PFO. There have been some studies suggesting that older patients with PFOs have a higher rate of a certain type of stroke (called paradoxical thromboembolic stroke). The reason for this is that older people frequently develop blood clots in the veins in their legs. These clots can sometimes travel from their original site to the right side of their heart.

  If a PFO is present, the clot can then pass from the right side to the left side and may travel to the brain and become lodged there, preventing blood flow to that part of the brain (stroke).

  Some patients may take medication to prevent blood clots.

• Calling your health care provider

  Call your health care provider if your baby turns blue when crying or defecating. Usually, however, this disorder is only discovered incidentally when a cardiologist performs an echocardiogram (ultrasound of the heart) to evaluate an unrelated heart murmur.

Review Date: 12/28/2009

Reviewed By: David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc., and Kurt R. Schumacher, MD, Pediatric Cardiology, University of Michigan Congenital Heart Center, Ann Arbor, MI. Review provided by VeriMed Healthcare Network.