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Health Encyclopedia

Health Encyclopedia

An invaluable resource of health information.

Xanthoma

Xanthoma is a skin condition in which fat builds up under the surface of the skin.

  • Alternative Names

    Skin growths - fatty; Xanthelasma

  • Causes, incidence, and risk factors

    Xanthomas are common, particularly among older adults and people with high blood lipids.

    Xanthomas vary in size. Some are very small, while others are bigger than 3 inches in diameter. They may appear anywhere on the body, but are most often seen on the elbows, joints, tendons, knees, hands, feet, or buttocks.

    They may be a sign of a medical condition that involves an increase in blood lipids. Such conditions include:

    Xanthelasma palpebra, a common type of xanthoma that appears on the eyelids and may occur without any underlying medical condition, is not necessarily associated with elevated cholesterol or lipids.

  • Symptoms

    A xanthoma looks like a sore or bump under the skin. It's usually flat, soft to the touch, and yellow in color. It has sharp, distinct edges.

  • Signs and tests

    Your health care provider will examine the skin. Usually, a diagnose of xanthoma can be made by looking at your skin. A biopsy of the growth will show a fatty deposit.

    You may have blood tests done to check lipid levels, liver function, and for diabetes.

  • Treatment

    If you have a disease that causes increased blood lipids, treating the condition may help reduce the development of xanthomas.

    If the growth bothers you, your doctor may remove it. However, xanthomas may come back after surgery.

  • Expectations (prognosis)

    The growth is non-cancerous and painless, but may be a sign of another medical condition.

  • Complications

    The growth may cause a change in how you look. This is called cosmetic disfiguring.

  • Calling your health care provider

    Call your health care provider if xanthomas develop. They may indicate an underlying disorder that needs treatment.

  • Prevention

    Control of blood lipids, including triglycerides and cholesterol levels, may help to reduce development of xanthomas.

  • References

    Errors in Metabolism. James WD, Berger TG, Elston DM, eds. Andrews' Diseases of the Skin: Clinical Dermatology. 10th ed. Philadelphia, Pa: Saunders Elsevier; 2005: chap 26.

    Massengale WT, Nesbitt LT Jr. Xanthomas. In: Bolognia JL, Jorizzo JL, Rapini RP, eds.: Dermatology. 2nd ed. Philadelphia, Pa: Mosby Elsevier; 2008: chap 91.

    Semenkovich CF. Disorders of Lipid Metabolism. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier. 2007: chap 217.

Review Date: 8/26/2009

Reviewed By: Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network; Linda Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2014 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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